Simplex’s single-stranded DNA ladders function the same way as typical double-stranded DNA ladders, except they are ideal for any experiment or procedure involving single-stranded DNA or RNA. Single-stranded and double-stranded oligonucleotides have different electrophoretic mobility characteristics, so an appropriate ladder of the same type enables more accurate sizing. For researchers working with single-stranded oligonucleotides, our single-stranded DNA ladders will be ideal for you.

Who USES Simplex’s LADDERS?

Single-stranded DNA ladders from Simplex Sciences have been used by some of the largest pharmaceutical companies in the world. Additionally, Simplex’s single-stranded DNA ladders have been purchased by research universities from across the United States as well as in the U.K., South Korea, Australia, and Germany. Various biotechnology start-ups, agriculture companies, and other clients have also used Simplex’s single-stranded DNA ladders for their products.

HOW DO I USE SIMPLEX’s LADDERS?

All of our single-stranded DNA ladders are shipped with a product insert that includes detailed instructions on how to use our single-stranded DNA ladders. In general, Simplex’s single-stranded DNA ladders function best in polyacrylamide gel when stained with SYBR Gold Nucleic Acid Gel Stain. Each tube of our single-stranded DNA ladder products includes approximately 12-16 uses.